Metadate ER
Metadate ER is an extended-release tablet formulation of methylphenidate hydrochloride, a central nervous system (CNS) stimulant. Unlike its sibling product Metadate CD, which uses a bead-based capsule, Metadate ER is a wax-matrix or slow-release tablet designed to provide a steady, uniform release of medication. It is primarily used to manage symptoms of ADHD and narcolepsy by regulating neurotransmitters like dopamine and norepinephrine to improve focus, alertness, and impulse control. Because the tablets are designed to release medication over an 8-hour period, they must be swallowed whole and never crushed or chewed to prevent the dangerous, immediate release of the entire dose.
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Metadate ER is a central nervous system (CNS) stimulant that contains methylphenidate hydrochloride. It is formulated as an extended-release tablet that provides a steady release of medication throughout the day. Unlike Metadate CD, which combines both immediate-release and extended-release beads, Metadate ER delivers its dose in a single extended-release form.
What Are Side Effects of Metadate ER?
Common side effects of Metadate ER include:
- headache,
- stomach pain,
- loss of appetite,
- trouble sleeping (insomnia),
- dizziness,
- nausea,
- vomiting,
- weight loss,
- lightheadedness,
- irritability,
- nervousness,
- blurred vision or other vision problems,
- dry mouth,
- constipation,
- sweating,
- skin rash,
- hypersensitivity reactions (hives, fever, joint pain, skin peeling, skin redness, easy bruising or bleeding),
- numbness/tingling/cold in your hands or feet,
- nervous feeling,
- heart palpitations,
- difficulty moving (dyskinesia),
- blood pressure changes,
- fast heart rate,
- chest pain,
- abdominal pain, or
- (rarely) drowsiness.
Dosage for Metadate ER
The average dose of Metadate ER is 20 to 30 mg daily, divided into 2 or 3 doses, taken 30 to 45 minutes before meals. Some patients may require 40 to 60 mg/day, and in others 10 to 15 mg daily is adequate.
Metadate ER During Pregnancy or Breastfeeding
Metadate ER should be used only when prescribed during pregnancy. It is not known whether this drug passes into breast milk. Consult your doctor before breastfeeding.
Additional Information
Our Metadate ER (methylphenidate hydrochloride) Tablet Extended Release Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
















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