JWH-018: Synthetic Cannabinoid Overview & Safety Information
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JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.
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DESCRIPTION
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JWH 018 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively. For a CB1:CB2 ratio of 0.23.1 Its effects on suppression of spontaneous activity.
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Stimulant
Stimulants excite the nervous system and increase physiological function.
Research Chemical
Research chemicals are drugs
Dose Oral
Light 50-100mg
Common 100-200mg
Strong 200mg+
Duration Oral Hours
Onset Oral Minutes
After Effect 2-4 hours
| Weight : | 10g, 20g, 50g, 100g, 500g, 1kg |
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