Dextromethorphan Polistirex ER

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Dextromethorphan Polistirex ER is an extended-release medication that helps relieve persistent cough by acting on the brain’s cough center. It provides up to 12 hours of symptom control. Use only as prescribed, as side effects can include drowsiness, dizziness, nausea, and rare serious reactions like breathing problems or confusion.

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Product Information:

Dextromethorphan Polistirex ER is an extended-release cough suppressant used to temporarily relieve persistent or chronic cough.

  • Dextromethorphan: acts on the brain to reduce the urge to cough.

  • Polistirex: a polymer that slows absorption, allowing the medicine to work up to 12 hours for extended relief.

It does not treat infections; it only reduces cough symptoms.

How to Take:

  • Take exactly as prescribed by your doctor.

  • Extended-release capsules or liquid should not be crushed, chewed, or split, as this can release the drug too quickly.

  • Can be taken with or without food.

  • Do not combine with alcohol or other medicines that cause drowsiness unless approved by a doctor.

  • Take at the same times each day to maintain consistent symptom relief.

Dosage:

  • Adults and children ≥12 years: Often one extended-release dose every 12 hours as prescribed.

  • Children <12 years: Use only if specifically directed by a healthcare provider.

Warnings:

  • May cause drowsiness, dizziness, or confusion—avoid driving or operating machinery until you know how it affects you.

  • Do not use if allergic to dextromethorphan or any other ingredients.

  • Drug interactions: Avoid combining with MAO inhibitors, SSRIs, SNRIs, or other serotonergic drugs—can cause serotonin syndrome, a serious condition.

  • Use caution in liver or kidney disease.

  • Seek medical advice if cough lasts more than 7 days, worsens, or comes with fever, rash, or persistent headache.

Side Effects:

  • Drowsiness or dizziness

  • Nausea or upset stomach

  • Mild headache

  • Mild nervousness or restlessness

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