Efgartigimod (Vyvgart)

Efgartigimod (Vyvgart) Alfa-fcab Injection for Generalized Myasthenia Gravis (gMG)

Efgartigimod (Vyvgart) alfa-fcab injection is a prescription biologic therapy used to treat
generalized myasthenia gravis (gMG) in adults who are
anti-acetylcholine receptor (AChR) antibody positive.
It works by reducing pathogenic IgG antibodies that interfere with normal nerve-to-muscle communication.

What Is Efgartigimod Alfa-fcab Used For?

Efgartigimod alfa-fcab is indicated for the treatment of generalized myasthenia gravis,
a chronic autoimmune neuromuscular condition that causes muscle weakness, fatigue,
and impaired motor function.

Administration & Dosage

A trained healthcare professional administers efgartigimod alfa-fcab by intravenous (IV) infusion
in a clinical setting. Each infusion is given slowly over at least one hour.

• Typical dosing: once weekly for 4 consecutive weeks
• Administration: intravenous infusion (IV)
• Supervision: physician or qualified healthcare provider

Before Using Efgartigimod (Vyvgart) Medicine

Allergies

Inform your doctor about any known allergies to efgartigimod alfa-fcab or other medications.
Also disclose allergies to foods, dyes, preservatives, or animals.

Special Populations for Efgartigimod (Vyvgart)

• Pediatric: Safety and efficacy have not been established.
• Geriatric: No age-specific limitations have been identified.
• Breastfeeding: Use only if potential benefits outweigh potential risks.

Drug Interactions

Efgartigimod alfa-fcab may interact with certain medications, particularly
live vaccines and immunosuppressive therapies.
Live vaccines should be avoided during treatment unless approved by a healthcare provider.

Precautions & Warnings

Regular medical monitoring is required during treatment. Blood tests may be performed to assess safety.

• Increased risk of infections
• Possible infusion-related reactions
• Risk of serious allergic reactions, including anaphylaxis
• May cause low blood pressure (hypotension)

Possible Side Effects

Common Side Effects

• Urinary tract symptoms
• Cough or sore throat
• Muscle or joint pain
• Fever or flu-like symptoms

Serious Side Effects (Seek Medical Attention)

• Difficulty breathing or swallowing
• Swelling of the face, lips, tongue, or throat
• Dizziness or fainting
• Severe skin rash or hives

Important Safety Information

Do not receive vaccinations, especially live vaccines, during treatment unless approved by your doctor.
Avoid taking additional prescription, OTC, or herbal medicines without medical advice.

This medication is available only by prescription and must be administered in a medical facility.
Always follow your healthcare provider’s instructions.