Ketoprofen topical gel/patch

Ketoprofen topical gels and patches deliver localized anti-inflammatory and analgesic effects directly to affected tissues while minimizing systemic exposure. As a topical NSAID, ketoprofen inhibits cyclo-oxygenase (COX-1 and COX-2), reducing prostaglandin synthesis responsible for pain, swelling, and inflammation.

Topical delivery makes ketoprofen particularly suitable for musculoskeletal pain, sports injuries, and osteoarthritis where oral NSAIDs may be contraindicated or poorly tolerated.

Key Benefits

• Targeted anti-inflammatory pain relief

• Lower systemic NSAID exposure vs oral formulations

• Effective for acute and chronic musculoskeletal conditions

• Available in gel and transdermal patch forms

Common Indications

• Osteoarthritis (knees, hands, joints)

• Muscle strains and sprains

• Sports injuries

• Tendinitis and bursitis

• Localized soft-tissue inflammation

• Post-traumatic pain

Mechanism of Action

Ketoprofen inhibits cyclo-oxygenase enzymes, decreasing prostaglandin production at the site of application. This results in reduced inflammation, swelling, and pain without significant central nervous system effects.

Dosage Forms & Strengths

• Topical Gel: Commonly 2.5%–5%

• Topical Patch: Sustained-release NSAID delivery (strength varies by manufacturer)