Taurosept Taurolodine

Taurolidine could be a broad spectrum antibiotic that was derived from the aminosulfoacid Taurine. Shown to be effective against aerobic, anaerobic, gram-negative and gram-positive bacterium likewise as fungi and mycobacteria. Found to exhibit antitumor activity with low toxicity, antiangiogenic effects, antiendotoxin activity, and to induce apoptosis of tumour cells; thereby decreasing proliferation of the tumour cells (both in vitro and in vivo). Has been utilized in studies of other chemotherapeutics, and is shown to work synergistically with rhTRAIL doubling the consequences of Taurolidine alone. The synergistic response of Taurolidine and trail might define a new therapeutic strategy in oncology medical care.