Skyrizi Injection

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Skyrizi (risankizumab) is a biologic injection used to treat moderate-to-severe plaque psoriasis. It targets IL-23 to reduce inflammation and skin symptoms. Given under the skin every few weeks, it may cause injection-site reactions, infections, fatigue, or headache. Use under medical supervision with proper precautions.

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Product Information:

  • Type of medication: Skyrizi is a biologic drug (monoclonal antibody) used to treat moderate-to-severe plaque psoriasis, a skin condition that causes red, scaly patches.

  • How it works: It targets a protein called IL-23, which is involved in inflammation, helping reduce psoriasis symptoms.

How Skyrizi is Taken:

  • Form: Skyrizi is given as a subcutaneous injection (under the skin).

  • Schedule: Usually:

    • First dose: Week 0

    • Second dose: Week 4

    • Then: Every 12 weeks (maintenance)

  • Administration: Can be injected by a healthcare professional or at home if trained.

  • Important: Use exactly as prescribed; do not change the dose or schedule.

Warnings:

  1. Infections: Skyrizi can weaken your immune system. Avoid exposure to tuberculosis (TB) and other infections.

  2. Allergic reactions: Rare but serious reactions can occur after injection.

  3. Vaccines: Avoid live vaccines while on Skyrizi.

  4. Pregnancy / breastfeeding: Should be discussed with your doctor.

Side Effects:

  • Redness, pain, or swelling at the injection site

  • Upper respiratory infections (cold-like symptoms)

  • Fatigue

  • Headache

  • Itching

Serious side effects (contact a doctor immediately):

  • Signs of infection (fever, cough, sore throat)

  • Severe allergic reaction (rash, swelling, trouble breathing)

Skyrizi is effective for controlling psoriasis but must be used under medical supervision to manage risks and monitor for side effects.

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